王应祥

华南农业大学生命科学学院教授

岭南现代农业科学与技术广东省实验室 研究员

生命科学学院 院长

广东省农业生物发育与环境适应重点实验室 主任

南方大豆创新研究院 执行院长

电子邮箱:yxwang@scau.edu.cn




研究兴趣

1.大豆适应热带亚热带的分子遗传基础和新种质创制

2.植物生殖发育的遗传和表观遗传调控机制


教育经历

1998-2007    华南农业大学获农学学士和博士学位


工作经历

2007-2011    华南农业大学和复旦大学 博士后

2004-2005和2013-2014    宾州州立大学 访问学者

2011-2015    复旦大学生命科学学院 副研究员

2015-2022    复旦大学生命科学学院  教授

2022至今     华南农业大学生命科学学院 教授/岭南现代农业科学与技术广东省实验室 研究员


社会兼职

Senior Editor in Seed Biology

Associate Editor in Reproduction and Breeding

植物学报 编委

华南农业大学学报自然科学版 副主编

中国植物学会植物结构与生殖生物学专业委员会副主任

中国细胞生物学学会植物细胞委员会副会长

中国植物生理与植物分子生物学学会理事

广东省生物化学与分子生物学常务理事


研究领域和成果 

        申请人一直致力于聚焦植物生殖发育、大豆适应热带亚热带的分子遗传机制及新种质创新研究,取得的主要成果迄今在Annual Review of  Plant Biology、Nature Plants、Plant Cell、PNAS等杂志共发表SCI论文和综述80余篇。

       获上海市青年科技启明星计划、教育部国家重点人才工程(国内)、国家基金委“杰出青年”基金、国务院政府特殊津贴,入选复旦大学“卓学”和“卓识” 人才计划;获广东省教学特等奖(本科类)、广东省教学二等奖(研究生类)、指导学生获iGEM获金奖和生命学科全国竞赛一等奖等。


代表性论文和论著

1. Chang Y#, Chen Z#, Chen W#, Jin X, Wang X, Zhan H, Cao L, Wang H, Wang YX*, Wang C*, Sun B*. KNUCKLES promotes meiotic cell cycle progression by directly repressing the expression of KRP1 and KRP3 to ensure male fertility. Plant Commun. 2025. doi: 10.1016/j.xplc. 2025.101610.

2. Lian Q*, Jiao W*B, Wang YX*.Designing better crops with phased pangenomes. Mol Plant. S1674-2052(25)00299-0.

3. Fang Y, Han Y, Fang Y, Sun J, Lin C, Bukhari B, Zhou D, Liu B, Guo CK*, Wang YX*. Epigenetic regulation modulates seasonal temperature-dependent growth of soybean in southern China. Plant Biotechnol J. 2025; 23(10):4580-4601.

4. Liu M, Fang Y, Jiang J, Chen H, Yang B, Xu X, Liu G, Ling C, Dong Z, Yang C*, Wang YX*. Natural variation in histone demethylase GmLDL2 confers flowering time divergence for geographical expansion in soybean. Nat Commun. 2025;16(1):5687.

5. Xu J, Zhou L, Chen K, Huang R, Niu B, Ye J, Ma H, Copenhaver GP, Wang YX*. ANAPHASE-PROMOTING COMPLEX/CYCLOSOME coactivators maintain AURORA1 kinase homeostasis during meiotic chromosome segregation. Plant Cell. 2025:koaf089.

6. Xu WY, Yu Y, Jing JL, Wu Z, Zhang XM, You CJ, Ma H, Copenhaver GP, He Y, Wang YX*. SCFRMF mediates degradation of the meiosis-specific recombinase DMC1. Nature Communications. 2023 14(1):5044

7. Wang TY, Wang HK, Lian QC,Jia Q, You CJ, Copenhaver GP*. Wang C*, Wang YX*. HEI10 is Subject to Phase Separation and Mediates RPA1a Degradation during Meiotic Interference-sensitive Crossover Formation. PNAS, 2023, Dec 26;120(52):e2310542120.

8. Li JC#, Wang C#, Liang W, Zhang J, Jiang CK, Liu Y, Ren Z, Ci D, Chang J, Han S, Deng    XW, Wang YX*, Qian WQ*. Functional importance and divergence of plant apurinic/apyrimidinic endonucleases in somatic and meiotic DNA repair. Plant Cell. 2023 35:2316-2331

9. Wang C#, Huang J, Li Y, Zhang J, He C, Li T, Jiang DH, Dong AW, Ma H*, Copenhaver GP*. Wang YX*.DNA Polymerase Epsilon Binds Histone H3.1-H4 and Recruits MORC1 to Mediate Meiotic Heterochromatin Condensation. PNAS, 2022, 119(43): e2213540119.

10. Wang C, Huang J, Zhang J, You Y, Copenhaver GP. You CJ*, Wang YX*. DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot in Arabidopsis, PNAS, 2022, 119(43): e2208441119.

11. Xian P, Cai Z, Jiang B, Xia Q, Cheng Y, Yang Y, Zhou Q, Lian T, Ma Q, Wang Y*, Ge L*, Nian H*. GmRmd1 encodes a TIR-NBS-BSP protein and confers resistance to powdery mildew in soybean. Plant Commun. 2022, Aug 10:100418. doi: 10.1016.

12. He C#, Chen Z#, Zhao Y, Yu Y, Wang H, Wang C, Copenhaver GP, Qi J*, Wang YX*.Histone demethylase IBM1-mediated meiocyte gene expression ensures meiotic chromosome synapsis and recombination. PLoS Genet. 2022 18:e1010041.

13. Li X, Zhang J, Huang J, Xu J, Chen Z, Copenhaver GP, Wang YX*. Regulation of interference-sensitive crossover distribution ensures crossover assurance in Arabidopsis. PNAS. 2021 118:e2107543118.

14. Chen H#, He C#, Wang C#, Wang X, Ruan F, Yan J, Yin P, Wang YX*, Yan SP*. RAD51 supports DMC1 by inhibiting the SMC5/6 complex during meiosis. Plant Cell. 2021 Aug 31;33(8):2869-2882.

15. Fang XL, Han YP, Liu MS, Jiang JC, Li X, Lian QC, Xie XR, Huang Y, Ma QB, Nian H, Qi J, Yang CY*, Wang YX*. Modulation of Evening Complex Activity Enables North-to-South Adaptation of Soybean. SCIENCE CHINA Life Sciences, 2020, (Cover story) 中国科学生命科学专文点评

16. Wang J#, Yu CY#, Zhuang SB, Ye JY, Dai H, Wang HK, Huang JY, Cao XF, Ma JB*, Ma H*, Wang YX*. Cell-type-dependent histone demethylase specificity promotes meiotic chromosome condensation in Arabidopsis. Nature Plants, 2020, 10.1038/s41477-020-0697-0.

17. Wang HK#, Xu WY#, Sun YJ, Lian QC, Wang C, Yu CY, He CP, Wang J, Ma H, Copenhaver GP*, Wang YX*. The cohesin loader SCC2 contains a PHD finger that is required for meiosis in land plants. PLoS Genetics, 2020, doi.org/10.1371/journal.pgen.1008849.

18. Xu RY#, Xu J#, Wang LD#, Niu BX, Copenhaver GP, Ma H, Zheng BL, Wang YX*. The Arabidopsis anaphase promoting complex/cyclosome subunit 8 is required for male meiosis. New Phytologist, 2019, 224(1):229-24.

19. Huang JY#, Wang C#, Wang HF, Lu PL, Zheng BL, Ma H, Copenhaver GP, Wang YX*. Meiocyte-specific and AtSPO11-1-dependent small RNAs and their association with meiotic gene expression and recombination. Plant Cell, 2019, 31:1-21. In brief by the editor in the same issue.

20. Xue M#, Wang J#, Jiang LG, Wolfe S, Pawlowskic WP*, Wang YX*, He Y* (2018) The number of meiotic double-strand breaks influences crossover distribution in Arabidopsis. Plant Cell, 2018, 30: 2628-2638,

21. Wang YX*, Copenhaver GP*. Meiotic Recombination: Mixing It Up in Plants. Annual Review Plant Biology. 2018, 69: 577-609

22. Su H#, Chen ZH#, Huang JY, Lin J, Copenhaver GP, Ma H, Wang YX*. Arabidopsis RAD51, RAD51C and XRCC3 proteins form a complex and facilitate RAD51 localization on chromosomes for meiotic recombination. PLoS Genetics, 2017, e1006827. doi: 10.1371

23. Wang J, Niu BX, Huang JY, Wang HK, Yang XH, Dong AW, Mackaroff C, Ma H, Wang YX*. Arabidopsis MMD1 Ensures the Progression of Male Meiotic Chromosome Condensation and Directly Regulates the Expression of Condensin Gene CAP-D3. Plant Cell. 2016, 28:1894-1909.

24. Niu BX#, Wang LD#, Zhang LS, Ren D, Ren R, Copenhaver GP, Ma H*, Wang YX*. The Arabidopsis CDC20.1 Gene is Required for Normal Meiotic Spindle Assembly and Chromosome Segregation. Plant Cell. 2015, 27:1-16.

25. Huang JY#, Cheng ZH#, Wang C, Hong Y, Su H, Wang H, Copenhaver GP, Ma H*, Wang YX*. Formation of interference-sensitive meiotic crossovers requires sufficient DNA leading strand elongation. PNAS, 2015, 112:12534-9.