Name:Jun Jiang

E-mail:jiangjun@scau.edu.cn

Tel:+86-20-85201331

Address:

Collegeof Life Sciences

SouthChina Agricultural University

483Wushan Road, Tianhe District

Guangzhou,Guangdong 510642

People'sRepublic of China

Education

Bachelor,Biological Sciences, Central China Normal University, China, 2004  

Doctor,Genetics, Institute of Hydrobiology, Chinese Academy of Sciences,China, 2009

ScientificTraining/positions

PostdoctoralResearch Fellow, South China Agricultural University, China(2009-2011)

SeniorResearch Assistant, LKS Faculty of Medicine, The University of HongKong, China (2011)

AssociateProfessor, South China Agricultural University, China (2011-present)

Visitingscholar, University of California, Irvine, USA (2019-2020)

Researchinterest

• Thedevelopment, prevention and control mechanisms of mycotoxicoses

• Thefunction, structure and transcriptional regulation of enzymes(especially cytochrome P450s) involved in the biotransformation ofmycotoxins

RepresentativePublications (*corresponding author; ^#co-firstauthor)

1. QianLiu, Jikai Wen, Jiahui Zhu, Tingting Zhang, YiqunDeng*, Jun Jiang*.Aromatic Hydrocarbon Receptor Regulates Chicken Cytochrome P450 1A5Transcription: A Novel Insight into T-2 Toxin-induced GeneExpression and Cytotoxicity in LMH Cells. BiochemicalPharmacology. 2019 Oct; 168: 319-329.

2. HaoranJiang, Jun Wu, Feiyong Zhang, Jikai Wen, JunJiang*, Yiqun Deng*. The critical roleof porcine cytochrome P450 3A46 in the bioactivation of aflatoxinB₁. BiochemicalPharmacology. 2018 Oct; 156: 177-185.

3. JunJiang^#,Shulin Tang^#,Jianhong Xia, Jikai Wen, Shuang Chen, Xiaodong Shu, Michael S. Y.Huen, Yiqun Deng*. C9orf140, a novel Axin1-interacting protein,mediates the negative feedback loop of Wnt/β-catenin signaling.Oncogene. 2018May; 37: 2992-3005.   

4. LinfengDong, Qingmei Chen, Xin Liu, Jikai Wen, JunJiang*, Yiqun Deng*. Role of SpecificityProtein 1, Hepatocyte Nuclear Factor 1α, and Pregnane X Receptor inthe Basal and Rifampicin-Induced Transcriptional Regulation ofPorcine Cytochrome P450 3A46. DrugMetabolism and Disposition. 2015 Oct;43(10): 1458-1467.  

5. QiYang, Shulin Tang, Linfeng Dong, Qingmei Chen, Xin Liu, JunJiang*, Yiqun Deng*. Transcriptionalregulation of chicken cytochrome P450 2D49 basal expression byCCAAT/enhancer-binding protein α and hepatocyte nuclear factor 4α.FEBS Journal.2014 Mar; 281(5): 1379-1392.   

6. ShirleyM.H. Sy^#, JunJiang^#,Wai Sum O, Yiqun Deng*,Michael S.Y. Huen*. The Ubiquitin Specific Protease USP34 PromotesUbiquitin Signaling at DNA Double-Strand Breaks. NucleicAcids Research. 2013Oct; 41(18): 8572-8580.

7. HuaCai^#, JunJiang^#,Qi Yang, Qingmei Chen, Yiqun Deng*. Functional Characterization of aFirst Avian Cytochrome P450 of the CYP2D Subfamily (CYP2D49). PLoSOne. 2012 Jun 4; 7(6): e38395.  

8. JiansheWang^#, JunJiang^#,Hongxia Zhang, Junping Wang, Hua Cai, Cheng Li, Kangbai Li, JingLiu, Xuejiang Guo, Guangxun Zou, Dazhi Wang, Yiqun Deng*, JiayinDai*.Integratedtranscriptional and proteomic analysis with invitro biochemical assay reveal the importantrole of CYP3A46 in T-2 toxin hydroxylation in porcine primaryhepatocytes. Molecular &Cellular Proteomics.2011 Sep; 10(9):M111.008748, 1-18.   

9. ShirleyM.-H. Sy^#, JunJiang^#,Sui-sui Dong, Gabriel Tsz-Mei Lok, Jun Wu, Hua Cai, Enoch S.L.Yeung, Jun Huang, Junjie Chen, Yiqun Deng*, Michael S.Y. Huen*.Critical roles of ring finger protein RNF8 in replication stressresponses. Journal of BiologicalChemistry. 2011 Jun 24; 286(25):22355-22361.

10. JunJiang^#,Junping Wang^#,Hua Cai, Kangbai Li, Yiqun Deng*. CYP3As catalyze nifedipineoxidation in pig liver microsomes: enzyme kinetics, inhibition andfunctional expression. CatalysisCommunications. 2011 Mar 31; 12(8):694-697.