Associate professor Jin-Cheng Ma
College of Life Science,
Guangdong Provincial Key Laboratory of Protein Function and Regulation in Agricultural Organisms,
South China Agricultural University,
Guangzhou, 510642, P. R. China
Tel: +86-20-85281389
E-mail: majincheng@scau.edu.cn
Education
March, 2016 One-year Visiting Scholar, Iowa State University, ISU, USA
June, 2009 Ph. D. in Biochemistry and Molecular Biology, Southwest University, Chongqing, China. Advisor: Prof. Pei Yan.
June, 2002 B. S. in Plant Protection. Southwest Agricultural University, Chongqing, China.
Professional Biography
My primary responsibilities are in undergraduate teaching. I teach Microbiology (8151090, 4 credits) each fall semester for biotechnology and biological science majors, Virology (8153097, 2 credits) each spring semester for biological science majors.
My research interests are on biochemical metabolism and pathogenic molecular mechanism of pathogenic microorganisms. Our group focuses on the diversity of bacterial fatty acid synthesis metabolism and its relationship to pathogenicity of some pathogenic bacteria, such as Pseudomonas aeruginosa, Enterococcus faecalis, Ralstonia solanacearum and Xanthomonas campestris and Pseudomonas syringae. We also conduct research on how to divert the intermediates of fatty acid synthesis to other end products such as quorum-sensing (QS) molecules AHLs or diffusible signal factor (DSF), lipid A, rhamnolipid, lipoic acid in pathogenic bacteria. It is expected that these research will provide some references for discovering new target to inhibit bacteria growth and developing novel antibacterial agents to effectively control pathogenic bacteria infection.
Area of Expertise
Fatty acid biosynthesis; Quorum sensing; Bacterial interactions with plants.
Selected Publications |
Yu Y, Ma J, Guo Q, Ma J, Wang H. A novel 3-oxoacyl-ACP reductase (FabG3) is involved in the xanthomonadin biosynthesis of Xanthomonas campestris pv. campestris. Mol. Plant Pathol., 2019, 20: 1696-1709. Guo Q-Q, Zhang W-B, Zhang C, Song Y-L, Liao Y-L, Ma J-C, Yu Y-H, Wang H-H. Characterization of 3-Oxacyl-Acyl Carrier Protein Reductase Homolog Genes in Pseudomonas aeruginosa PAO1. Frontiers in Microbiology, 2019, 10. Hu Z, Dong H, Ma J C, Yu Y, Li K H, Guo Q Q, Zhang C, Zhang W B, Cao X, Cronan J E, Wang H. Novel Xanthomonas campestris Long-Chain-Specific 3-Oxoacyl-Acyl Carrier Protein Reductase Involved in Diffusible Signal Factor Synthesis. MBio, 2018, 9. Sun Y, Zhang W, Ma J, Pang H, Wang H. Overproduction of alpha-Lipoic Acid by Gene Manipulated Escherichia coli. PLoS One, 2017, 12: e0169369. Ma J C, Wu Y Q, Cao D, Zhang W B, Wang H H. Only Acyl Carrier Protein 1 (AcpP1) Functions in Pseudomonas aeruginosa Fatty Acid Synthesis. Front Microbiol, 2017, 8: 2186. Li K-H, Yu Y-H, Dong H-J, Zhang W-B, Ma J-C, Wang H-H. Biological Functions of ilvC in Branched-Chain Fatty Acid Synthesis and Diffusible Signal Factor Family Production in Xanthomonas campestris. Frontiers in Microbiology, 2017, 8 Feng S, Xu C, Yang K, Wang H, Fan H, Liao M. Either fadD1 or fadD2, Which Encode acyl-CoA Synthetase, Is Essential for the Survival of Haemophilus parasuis SC096. Front Cell Infect Microbiol, 2017, 7: 72. Yu Y H, Hu Z, Dong H J, Ma J C, Wang H H. Xanthomonas campestris FabH is required for branched-chain fatty acid and DSF-family quorum sensing signal biosynthesis. Sci Rep, 2016, 6: 32811. Mao Y H, Li F, Ma J C, Hu Z, Wang H H. Sinorhizobium meliloti Functionally Replaces 3-Oxoacyl-Acyl Carrier Protein Reductase (FabG) by Overexpressing NodG During Fatty Acid Synthesis. Mol Plant Microbe Interact, 2016, 29: 458-467. Huang Y H, Lin J S, Ma J C, Wang H H. Functional Characterization of Triclosan-Resistant Enoyl-acyl-carrier Protein Reductase (FabV) in Pseudomonas aeruginosa. Front Microbiol, 2016, 7: 1903.
|
