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Working Experience:
Sep, 2014 – Present | 华南农业大学，教授，独立课题组组长 South China Agricultural University, Guangzhou, China Professor & Principle Investigator |
Dec, 2010 Aug, 2014 | 美国约翰斯霍普金斯大学 & 香港中文大学，博士后研究员 Johns Hopkins University, Baltimore, MD, USA & The Chinese University of Hong Kong, Hong Kong Postdoctoral Research Scientist |
Education:
Aug, 2006 – Oct, 2010 | 博士，香港中文大学，细胞与分子生物学 Ph.D., The Chinese University of Hong Kong, Hong Kong (Cell and Molecular Biology) |
Aug, 2003 – July, 2006 | 硕士，兰州大学，分子生物学 M.Sc., Lanzhou University, China (Molecular Biology) |
Aug, 1999 – July, 2003 | 学士，兰州大学，生物科学 B.Sc., Lanzhou University, China (Biology) |
Research Interests:
1. 植物细胞与分子生物学
2. 细胞自噬与植物雄性育性
3. 细胞器生物发生与功能
4. 植物生物技术与生物反应器
Publications:
2024:
34. Zhen Lu#, He Yan# (co-first author) and Hao Wang* (2024) Autophagy modulates male fertility in Arabidopsis. Autophagy, DOI:10.1080/15548627.2024.2441305.
34. He Yan#, Zhen Lu#(co-first author), Xiaojuan Du, Zhengtao You, Mingkang Yang, Nianle Li, Xuequan Li, Zailue Ni, Hong Wu, Xiangfeng Wang, Lifeng Zhao and Hao Wang* (2024) Autophagy modulates Arabidopsis male gametophyte fertility by controlling actin organization. Nature Communications, DOI: doi: 10.1038/s41467-024-54468-8.
33. Xun Weng and Hao Wang* (2024) Quantifying Protein Dynamics in Growing Pollen Tubes using Kymograph Analysis. Methods in Molecular Biology 2841, 131-143.
32. He Yan#, Ao Qi#(co-first author), Zhen Lu#(co-first author), Zhengtao You# (co-first author), Ziheng Wang, Haiying Tang, Xinghai Li, Qiao Xu, Xun Weng, Xiaojuan Du, Lifeng Zhao and Hao Wang* (2024) Dual roles of AtNBR1 in regulating selective autophagy via liquid-liquid phase separation and recognition of non-ubiquitinated substrates in Arabidopsis. Autophagy, DOI: 10.1080/15548627.2024.2391725.
31.Xiaojuan Du#, Xun Weng# (co-first author), Binyang Lyu, Lifeng Zhao and Hao Wang* (2024) Localized calcium transients in phragmoplast regulate cytokinesis of tobacco BY-2 cells. Plant Cell Reports 43, DOI: https://doi.org/10.1007/s00299-024-03181-3
30.Xiaojuan Du, Yingmiao Gao, Hao Zhang, Xiaoyu Xu, Ying Li, Lifeng Zhao*, Ming Luo* and Hao Wang* (2024) HDA6 modulates Arabidopsis pavement cell morphogenesis through epigenetic suppression of ROP6 GTPase expression and signaling. New Phytologist 241, 2523-2539.
2023:
29.Xun Weng, Yifan Shen, Liwen Jiang, Lifeng Zhao*, Hao Wang* (2023) Spatiotemporal organization and correlation of tip-focused exocytosis and endocytosis in regulating pollen tube tip growth. Plant Science330, 111633.
28.Jean-Marc Neuhaus*, Peter Pimpl*, Qiong Zhao* and Hao Wang* (2023) Editorial: Regulation of plant organelle biogenesis and trafficking. Frontiers in Plant Science, DOI: 10.3389/fpls.2023.1211807.
2022:
27.Xun Weng and Hao Wang* (2022) Apical vesicles: social networking at the pollen tube tip.Reproduction and Breeding99, 536-555.
26.He Yan, Menglong Zhuang, Xiaoyu Xu, Shanshan Li, Mingkang Yang, Nianle Li, Xiaojuan Du, Kangwei Hu, Xiaomin Peng, Wei Huang, Hong Wu, Yu Chung Tse, Lifeng Zhao, Hao Wang* (2022) Autophagy and its mediated mitochondrial quality control maintain pollen tube growth and male fertility in Arabidopsis. Autophagy, DOI: https://doi.org/10.1080/15548627.2022.2095838.
25.Zhengjiang Xu, Mei Yang, Zhaoyang Li, Jian Xiao, Xueqing Yang, Hao Wang and Xiaofeng Wang* (2022) Tissue-specific pectin methylesterification and pectin methylesterase activities play a role in lettuce seed germination. Scientia Horticulturae 301,111134.
2020:
24.Lifeng Zhao, Muhammad Saad Rehmani and Hao Wang* (2020) Exocytosis and endocytosis: yin-yang crosstalk for sculpting a dynamic growing pollen tube tip. Frontiers in Plant Science, DOI: 10.3389/fpls.2020.572848.
2019:
23.Shanshan Li, He Yan, Wei-Ming Mei, Yu Chung Tse* and Hao Wang* (2019) Boosting autophagy in sexual reproduction: a plant perspective. New Phytologist 226,679-689.
22.Guolan Liu, Weiyuan Yang, Xiaojing Zhang, Tao Peng, Yi Zou, Tao Yang, Hao Wang, Xuncheng Liu, Li-zhen Tao* (2019) Cystathionine beta-lyase is crucial for embryo patterning and the maintenance of root stem cell niche in Arabidopsis. Plant Journal 99, 536-555.
2018:
21.Hao Wang#, Qiong Zhao# (co-first author), Jiaxin Fu, Xiangfeng Wang and Liwen Jiang* (2018) Re-assessment of biolistic transient expression: an efficient and robustmethod for protein localization studies in seedling-lethal mutant and juvenile plants. Plant Science 274, 2-7.
This article is highlighted as 2019 journal cover of Plant Science.
20.Xiaomin Peng, Shanshan Li and Hao Wang* (2018) Time bomb for pollen tubes: peptide RALF-1 mediated signaling. Molecular Plant 11, 518-520.
19.Xiaomin Peng#, Guitao Zhong# (co-first author) and Hao Wang* (2018) Co-expression of multiple chimeric fluorescent fusion proteins in an efficient way in plants. Journal of Visualized Experiments, DOI:10.3791/57345.
2017:
18.Guitao Zhong, Qinlong Zhu, Yingxin Li, Yaoguang Liu and Hao Wang* (2017) Once for all: a novel robust system for co-expression of multiple chimeric fluorescent fusion proteins in plants. Frontiers in Plant Science, DOI: 10.3389/fpls.2017.01071.
17.Guitao Zhong#, Ronghe Liu#, Menglong Zhuang and Hao Wang* (2017) Transient Expression of Chimeric Fluorescent Reporter Proteins in Pollen Tubes to Study Protein Polar Secretion and Dynamics. Methods in Molecular Biology 1662, 115-124.
16.Hao Wang* and Liwen Jiang* (2017) Polar protein exocytosis: lessons from plant pollen tube. In: Obermeyer G, Feijó J (eds) Pollen Tube Tip Growth: From Biophysical Aspects to Systems Biology, Springer Nature.
15.Huei-Jing Wang Wang, Ya-Wen Hsu, Cian-Ling Guo, Wann-Nang Jane, Hao Wang, Liwen Jiang and Guang-Yuh Jauh (2016) VPS36-Mediated MVB Formation is Critical for Plasmamembrane Protein Turnover and Vacuolar Biogenesis. Plant Physiology 173, 566-581.
2016:
14.Hao Wang, Xiaohong Zhuang, Xiangfeng Wang, Angus Ho Yin Law, Teng Zhao, Shengwang Du, Michael M. T. Loy and Liwen Jiang* (2016) A Distinct Pathway for Polar Exocytosis in Plant Cell Wall Formation. Plant Physiology 172, 1003-1018.
13.Teng Zhao, Sze Cheung Lau, Ying Wang, Yumian Su, Hao Wang, Aifang Cheng, Shengwang Du & M. M. T. Loy*(2016) Multicolor 4D Fluorescence Microscopy using Ultrathin Slit Bessel Light-sheets. Scientific Reports DOI: 10.1038/srep26159.
12.Hao Wang* (2016) Visualizing Plant Cells in A Brand New Way. Molecular Plant 9, 633-635.
Ph.D. and Postdoctoral Work:
11.Xiangfeng Wang#, Yi, Cai# (co-first author), Hao Wang, Yonglun Zheng, Xiaohong Zhuang, Baiying Li, and Liwen Jiang*. (2014) Trans-Golgi Network-Located AP1 Gamma Adaptins Mediate Dileucine Motif-Directed Vacuolar Targeting in Arabidopsis. The Plant Cell 26, 4102-4118.
10.Songshan Li, Qinghai He, Hao Wang, Xuming Tang, Kam Wing Ho, Xin Gao, Qian Zhang, Yang Shen, Annie Cheung, Francis Wong, Yung Hou Wong, Nancy Y. Ip, Liwen Jiang , Wing Hou Yung, Kai Liu*. (2014) Injured adult retinal axons with Pten and Socs3 co-deletion reform active synapses with suprachiasmatic neurons. Neurobiology of Disease 73, 366-376.
09.Hao Wang* and Liwen Jiang*. (2014) Immunofluorescence Labeling of Pollen Tubes. Bio-protocol 4 (10): http://www.bio-protocol.org/e1131.
08.Xiaohong Zhuang#, Hao Wang# (co-first author), Sheung Kwan Lam, Caiji Gao, Xiangfeng Wang, Yi Cai and Liwen Jiang (2013) A BAR-domain Protein SH3P2, binding to PI3P and ATG8, reveals and regulates the autophagosome formation in Arabidopsis thaliana.The Plant Cell 25, 4596-4615.
07.Hao Wang, Xiaohong Zhuang, Yi Cai, Alice Y. Cheung and Liwen Jiang* (2013) Apical F-Actin Regulated Exocytic Targeting of NtPPME1 is Essential for Pollen Tube Cell Wall Construction and Rigidity. Plant Journal 76, 367-379.
06.Liang-Zi Zhou, Sha Li, Qiang-Nan Feng, Yu-Ling Zhang ,Xinying Zhao, Yong-lun Zeng, Hao Wang, Liwen Jiang, and Yan Zhang* (2013) Protein S-ACYL Trasnferase10 Is Critical for Development and Salt Tolerance in Arabidopsis. The Plant Cell 25, 1093-1107.
05.Yi Cai, Xiaohong Zhuang, Junqi Wang, Hao Wang, Sheung Kwan Lam, Caiji Gao, Xiangfeng Wang and Liwen Jiang* (2012) Vacuolar Degradation of Two Integral Plasma Membrane Proteins, AtLRR84A and OsSCAMP1, Is Cargo Ubiquitination-Independent and Prevacuolar Compartment-Mediated in Plant Cells.Traffic 13, 1023-1040.
04.Hao Wang and Liwen Jiang* (2011) Transient Expression and Analysis of Fluorescent Reporter Proteins in Plant Pollens. Nature Protocols 6, 419-426.
03.Hao Wang, Xiaohong Zhuang, Stefan Hillmer, David G Robinson and Liwen Jiang (2011) Vacuolar Sorting Receptor (VSR) Proteins Reach the Plasma Membrane in Germinating Pollen Tubes. Molecular Plant 4, 845-853.
02.Hao Wang, John C Rogers and Liwen Jiang* (2011) Plant RMR proteins: Unique Vacuolar Sorting Receptors that Couple Ligand Sorting with Membrane Internalization. FEBS Journal 278, 59-68.
01.Hao Wang,Yu Chung Tse, Angus Ho Yin Law, Samuel Sai-ming Sun, Yongbin Sun, Zeng-fu Xu, Stefan Hillmer, David G Robinson and Liwen Jiang* (2010) Vacuolar Sorting Receptor (VSR) and Secretory Carrier Membrane Protein (SCAMP) are Essential for Pollen Tube Growth. Plant Journal 61, 826-838.
Grants:
1. 2024-2025, the Major Research Plan of the National Natural Science Foundation of China. (Co-PI)
国家自然科学基金重大研究计划（集成项目），共同主持。
2. 2023-2026, National Natural Science Foundation of China (NSFC). (PI)
国家自然科学基金面上项目，主持。
3. 2020-2023, the Major Research Plan of the National Natural Science Foundation of China. (PI)
国家自然科学基金重大研究计划（培育项目），主持。
4. 2021-2023, Natural Science Foundation of Guangdong Province, China. (PI)
广东省自然科学基金面上项目，主持。
5. 2018-2021, National Natural Science Foundation of China (NSFC).(PI)
国家自然科学基金面上项目，主持。
6. 2017-2019, Natural Science Foundation of Guangzhou, China. (PI)
广州市科技计划项目，主持。
7. 2016-2018, Natural Science Foundation of Guangdong Province, China. (PI)
广东省自然科学基金面上项目，主持。
8. 2016-2019, National Natural Science Foundation of China (NSFC). (PI)
国家自然科学基金面上项目，主持。
Professional Activities:
Associate Editor:
Frontiers in Plant Science;
Review Editor on Board:
Frontiers in Cell and Developmental Biology
学术委员会委员：中国电子显微镜学会共聚焦专业委员会，中国遗传学会细胞遗传分会。
Member: American Society of Plant Biologiests, International Congress on Sexual Plant Reproduction.
Teaching：
1. Cell Biology (Undergradaute Course)
2. Advanced Cell Biology (Postgradaute Course)
Awards Received by Graduate Students:
1. 2024 Annual Conference of Chinese Electron Microscopy Society Best Talk: WENG Xun
2024全国电子显微学学术年会优秀报告奖：翁洵
2. 2024 National Postgraduate Scholarship (1st class): LU Zhen
2024年国家一等奖学金：卢镇
3. 2023 SCAU Postgraduate Oversea Research Scholarship: WENG Xun
2023 年华南农业大学研究生短期海外访学奖学金：翁洵
4. 2022 SCAU Excellent Ph.D. Thesis: YAN He
2022年华南农业大学优秀博士毕业论文：闫河
5. 2017 SCAU Postgraduate Oversea Research Scholarship: LIU Jing
2017年华南农业大学研究生短期海外访学奖学金：刘晶
6. 2017 National Postgraduate Scholarship (1st class): ZHONG Guitao
2017年国家一等奖学金：钟桂涛
7. 2016 SCAU Postgraduate Oversea Research Scholarship: ZHONG Guitao
2017年华南农业大学研究生短期海外访学奖学金：钟桂涛
