胡 喆

发布者:生命科学学院发布时间:2022-03-16浏览次数:1539


   胡 喆

      首聘副教授      性别:男

      所属单位:微生物学系

      办公室:生命科学学院北-213

      Emailzhehu@scau.edu.cn




工作经历

2021.06至今,华南农业大学生命科学学院副教授

2017.05-2020.11,伊利诺伊大学厄巴纳-香槟分校(UIUC),微生物系,博士后


教育经历

2013.09-2016.12 理学博士,生物化学与分子生物学,华南农业大学

2010.09-2013.06 理学硕士,微生物学,华南农业大学

2006.09-2010.06 工学学士,生物工程,合肥工业大学


主讲课程

《微生物学》,《微生物学实验》。


研究领域

病原微生物脂肪酸及其衍生物代谢


科研项目

1 广东省基础与应用基础研究基金区域联合基金-青年基金项目 ,野油菜黄单胞菌3-酮脂酰ACP还原酶编码基因fabG2转录调控研究, 2021-102024-09,在研,主持。

2 华南农业大学高层次人才科研启动项目,2021-2026,在研,主持。


发表论文

1.Chen, Y.C., Hu Z#., Zhang W. B., Yin Y., Zhong C. Y., Mo W. Y., Yu Y.H., Ma J. C., and Wang H.H. 2022. Hetl-like phosphopantetheiny transferase posttranslationally modifies acyl carrier protein in Xanthomonas campestris. Mol Plant Microbe Interact, (accepted), Doi: org/10.1094/MPMO- 10-21-0240-R.

2.Hu Z., Ma J. C., Tong W.H., Zhu L., Wang H.H. and Cronan J.E. 2021. Escherichia coli FabG 3-ketoacyl-ACP reductase proteins lacking the assigned catalytic triad residues are active enzymes. J Biol Chem 296:100365.

3.Hu Z., and Cronan J. E. The primary step of biotin synthesis in Mycobacteria. 2020. Proc Natl Acad Sci USA 117(38): 23794-23801.

4.Srinivas S#., Hu Z#., and Cronan J. E. 2019. Escherichia coli vectors having stringently repressible replication origins allow streamlining of CRISPR/Cas9 gene editing. Plasmid103:53-62.

5.Hu Z, Dong H, Ma JC, Yu Y, Li KH, Guo QQ, Zhang C, Zhang WB, Cao X, Cronan JE, Wang H. 2018. Novel Xanthomonas campestris long-chain-specific 3-oxoacyl-acyl carrier protein reductase involved in diffusible signal factor synthesis. mBio 9:e00596-18.

6.Cao X.Y., Zhu L., Song X. J., Hu Z., and Cronan J. 2018. E. Protein moonlighting elucidates the essential human pathway catalyzing lipoic acid assembly on its cognate enzymes. Proc Natl Acad Sci USA 115(30): 7063-7072.

7.Cao X.Y., Zhu L., Hu Z., and Cronan J.E. 2017. Expression and Activity of the BioH Esterase of Biotin Synthesis is Independent of Genome Context. Sci Rep 7: 2141.

8.Yu Y, Hu Z, Dong H, Ma J, Wang H. 2016. Xanthomonas campestris FabH is required for branched-chain fatty acid and DSF-family quorum sensing signal biosynthesis. Sci Rep 6:32811.

9.Mao Y. H., Li F., Ma J. C., Hu Z. and Wang H. H. Functional replacement of 3-Oxoacyl-Acyl Carrier Protein Reductase (FabG) in fatty acid synthesis of Sinorhizobium meliloti by overexpression of NodG. Mol Plant Microbe Interact, 2016, 29(6): 458-467.

10.Feng S. X., Ma J. C., Yang J., Hu Z., Bi H. K., Sun Y. R. and Wang H. H. Ralstonia solanacearum fatty acid composition is determined by interaction of two 3-ketoacyl-acyl carrier protein reductases encoded on separate replicons. BMC microbiology,2015,15(1): 223, DOI 10.1186/s12866-015-0554-x.

11.Mao Y. H., Li F., Ma J. C., Hu Z. and Wang H. H. Ralstonia solanacearum RSp0194 Encodes A Novel 3-Keto-Acyl Carrier Protein Synthase III. Plos one, 2015, DOI: 10.1371/journal.pone.0136261.

12.马金成,周俊超,吴楚云,胡喆,王海洪。苜蓿中华根瘤菌desA基因功能的鉴定。生物化学与生物物理进展,201542(08)740-749

13.马金成,罗彪,胡喆,王海洪。乳酸乳球菌fabZ1fabZ2基因功能的鉴定.生物化学与生物物理进展,201441(08)777-786

14.胡喆,马金成,蒋晶晶,王海洪。苜蓿中华根瘤菌fabAfabB基因功能的鉴定。生物化学与生物物理进展,201340(11)1148-1159

15.Zhu L., Bi H., Ma J., Hu Z., Zhang W., Cronan J. E. and Wang H. The two functional enoyl-acyl carrier protein reductases of Enterococcus faecalis do not mediate triclosan resistance. mBio, 2013, 4(5): e00613-13.