王应祥

发布者:生命科学学院 发布时间:2022-04-01 浏览次数:17554



华南农业大学生命科学学院教授

岭南现代农业科学与技术广东省实验室 研究员

科学研究院 院长

广东省农业生物发育与环境适应重点实验室 主任

南方大豆创新研究院 执行院长

电子邮箱:yxwang@scau.edu.cn




研究兴趣

1.大豆适应热带亚热带的分子遗传基础和新种质创制

2.植物生殖发育的遗传和表观遗传调控机制


教育经历

1998-2007    华南农业大学获农学学士和博士学位


工作经历

2007-2011    华南农业大学和复旦大学 博士后

2004-2005和2013-2014    宾州州立大学 访问学者

2011-2015    复旦大学生命科学学院 副研究员

2015-2022    复旦大学生命科学学院  教授

2022至今     华南农业大学生命科学学院 教授/岭南现代农业科学与技术广东省实验室 研究员


社会兼职

Senior Editor in Seed Biology

Associate Editor in Reproduction and Breeding

植物学报 编委

华南农业大学学报自然科学版 副主编

中国植物学会植物结构与生殖生物学专业委员会副主任

中国细胞生物学学会植物细胞委员会副会长

中国植物生理与植物分子生物学学会理事

广东省生物化学与分子生物学常务理事


研究领域和成果 

        主要聚焦植物生殖发育、大豆适应热带亚热带的分子遗传机制及新种质创制研究,主要成果迄今在Annual Review of  Plant Biology、Nature Plants、Plant Cell、PNAS等杂志共发表SCI论文和综述80余篇。

       获上海市青年科技启明星计划、教育部国家重点人才工程(国内)、国家基金委“杰出青年”基金、国务院政府特殊津贴,入选复旦大学“卓学”和“卓识” 人才计划;获广东省教学特等奖(本科类)、广东省教学二等奖(研究生类)、指导学生获iGEM获金奖和生命学科全国竞赛一等奖等。


代表性论文和论著

1. Chang Y#, Chen Z#, Chen W#, Jin X, Wang X, Zhan H, Cao L, Wang H, Wang YX*, Wang C*, Sun B*. KNUCKLES promotes meiotic cell cycle progression by directly repressing the expression of KRP1 and KRP3 to ensure male fertility. Plant Commun. 2025. doi: 10.1016/j.xplc. 2025.101610.

2. Lian Q*, Jiao W*B, Wang YX*.Designing better crops with phased pangenomes. Mol Plant. S1674-2052(25)00299-0.

3. Fang Y, Han Y, Fang Y, Sun J, Lin C, Bukhari B, Zhou D, Liu B, Guo CK*, Wang YX*. Epigenetic regulation modulates seasonal temperature-dependent growth of soybean in southern China. Plant Biotechnol J. 2025; 23(10):4580-4601.

4. Liu M, Fang Y, Jiang J, Chen H, Yang B, Xu X, Liu G, Ling C, Dong Z, Yang C*, Wang YX*. Natural variation in histone demethylase GmLDL2 confers flowering time divergence for geographical expansion in soybean. Nat Commun. 2025;16(1):5687.

5. Xu J, Zhou L, Chen K, Huang R, Niu B, Ye J, Ma H, Copenhaver GP, Wang YX*. ANAPHASE-PROMOTING COMPLEX/CYCLOSOME coactivators maintain AURORA1 kinase homeostasis during meiotic chromosome segregation. Plant Cell. 2025:koaf089.

6. Xu WY, Yu Y, Jing JL, Wu Z, Zhang XM, You CJ, Ma H, Copenhaver GP, He Y, Wang YX*. SCFRMF mediates degradation of the meiosis-specific recombinase DMC1. Nature Communications. 2023 14(1):5044

7. Wang TY, Wang HK, Lian QC,Jia Q, You CJ, Copenhaver GP*. Wang C*, Wang YX*. HEI10 is Subject to Phase Separation and Mediates RPA1a Degradation during Meiotic Interference-sensitive Crossover Formation. PNAS, 2023, Dec 26;120(52):e2310542120.

8. Li JC#, Wang C#, Liang W, Zhang J, Jiang CK, Liu Y, Ren Z, Ci D, Chang J, Han S, Deng    XW, Wang YX*, Qian WQ*. Functional importance and divergence of plant apurinic/apyrimidinic endonucleases in somatic and meiotic DNA repair. Plant Cell. 2023 35:2316-2331

9. Wang C#, Huang J, Li Y, Zhang J, He C, Li T, Jiang DH, Dong AW, Ma H*, Copenhaver GP*. Wang YX*.DNA Polymerase Epsilon Binds Histone H3.1-H4 and Recruits MORC1 to Mediate Meiotic Heterochromatin Condensation. PNAS, 2022, 119(43): e2213540119.

10. Wang C, Huang J, Zhang J, You Y, Copenhaver GP. You CJ*, Wang YX*. DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot in Arabidopsis, PNAS, 2022, 119(43): e2208441119.

11. Xian P, Cai Z, Jiang B, Xia Q, Cheng Y, Yang Y, Zhou Q, Lian T, Ma Q, Wang Y*, Ge L*, Nian H*. GmRmd1 encodes a TIR-NBS-BSP protein and confers resistance to powdery mildew in soybean. Plant Commun. 2022, Aug 10:100418. doi: 10.1016.

12. He C#, Chen Z#, Zhao Y, Yu Y, Wang H, Wang C, Copenhaver GP, Qi J*, Wang YX*.Histone demethylase IBM1-mediated meiocyte gene expression ensures meiotic chromosome synapsis and recombination. PLoS Genet. 2022 18:e1010041.

13. Li X, Zhang J, Huang J, Xu J, Chen Z, Copenhaver GP, Wang YX*. Regulation of interference-sensitive crossover distribution ensures crossover assurance in Arabidopsis. PNAS. 2021 118:e2107543118.

14. Chen H#, He C#, Wang C#, Wang X, Ruan F, Yan J, Yin P, Wang YX*, Yan SP*. RAD51 supports DMC1 by inhibiting the SMC5/6 complex during meiosis. Plant Cell. 2021 Aug 31;33(8):2869-2882.

15. Fang XL, Han YP, Liu MS, Jiang JC, Li X, Lian QC, Xie XR, Huang Y, Ma QB, Nian H, Qi J, Yang CY*, Wang YX*. Modulation of Evening Complex Activity Enables North-to-South Adaptation of Soybean. SCIENCE CHINA Life Sciences, 2020, (Cover story) 中国科学生命科学专文点评

16. Wang J#, Yu CY#, Zhuang SB, Ye JY, Dai H, Wang HK, Huang JY, Cao XF, Ma JB*, Ma H*, Wang YX*. Cell-type-dependent histone demethylase specificity promotes meiotic chromosome condensation in Arabidopsis. Nature Plants, 2020, 10.1038/s41477-020-0697-0.

17. Wang HK#, Xu WY#, Sun YJ, Lian QC, Wang C, Yu CY, He CP, Wang J, Ma H, Copenhaver GP*, Wang YX*. The cohesin loader SCC2 contains a PHD finger that is required for meiosis in land plants. PLoS Genetics, 2020, doi.org/10.1371/journal.pgen.1008849.

18. Xu RY#, Xu J#, Wang LD#, Niu BX, Copenhaver GP, Ma H, Zheng BL, Wang YX*. The Arabidopsis anaphase promoting complex/cyclosome subunit 8 is required for male meiosis. New Phytologist, 2019, 224(1):229-24.

19. Huang JY#, Wang C#, Wang HF, Lu PL, Zheng BL, Ma H, Copenhaver GP, Wang YX*. Meiocyte-specific and AtSPO11-1-dependent small RNAs and their association with meiotic gene expression and recombination. Plant Cell, 2019, 31:1-21. In brief by the editor in the same issue.

20. Xue M#, Wang J#, Jiang LG, Wolfe S, Pawlowskic WP*, Wang YX*, He Y* (2018) The number of meiotic double-strand breaks influences crossover distribution in Arabidopsis. Plant Cell, 2018, 30: 2628-2638,

21. Wang YX*, Copenhaver GP*. Meiotic Recombination: Mixing It Up in Plants. Annual Review Plant Biology. 2018, 69: 577-609

22. Su H#, Chen ZH#, Huang JY, Lin J, Copenhaver GP, Ma H, Wang YX*. Arabidopsis RAD51, RAD51C and XRCC3 proteins form a complex and facilitate RAD51 localization on chromosomes for meiotic recombination. PLoS Genetics, 2017, e1006827. doi: 10.1371

23. Wang J, Niu BX, Huang JY, Wang HK, Yang XH, Dong AW, Mackaroff C, Ma H, Wang YX*. Arabidopsis MMD1 Ensures the Progression of Male Meiotic Chromosome Condensation and Directly Regulates the Expression of Condensin Gene CAP-D3. Plant Cell. 2016, 28:1894-1909.

24. Niu BX#, Wang LD#, Zhang LS, Ren D, Ren R, Copenhaver GP, Ma H*, Wang YX*. The Arabidopsis CDC20.1 Gene is Required for Normal Meiotic Spindle Assembly and Chromosome Segregation. Plant Cell. 2015, 27:1-16.

25. Huang JY#, Cheng ZH#, Wang C, Hong Y, Su H, Wang H, Copenhaver GP, Ma H*, Wang YX*. Formation of interference-sensitive meiotic crossovers requires sufficient DNA leading strand elongation. PNAS, 2015, 112:12534-9.