| 王聪，男，博士， 生命科学学院细胞与发育生物学系，首聘教授。 Email：wangc@scau.edu.cn |
研究兴趣及方向
以拟南芥和大豆为材料，围绕植物生殖发育环节细胞命运决定、减数分裂同源重组和表观遗传重编的分子机制等核心问题，结合多组学、细胞学、生物化学等手段从多维度解析调控花药发育和减数分裂的调控机制，加深对于遗传变异的认知，为农作物育种和人类生殖健康提供理论支持。主要研究方向为：1）植物减数分裂的命运决定和遗传调控；2）植物的表观遗传重编程；3）大豆花形态建成。以通讯或第一作者（含共同）在PNAS（3篇）、The Plant Cell（2篇）和Plant Physiology（2篇）等高水平期刊共发表论文12篇。获得国家自然科学基金面上项目（在研2项）、青年科学基金（2021-2023）和博士后创新人才（2019）的支持。受邀在全国植物生物学大会和发育生物学大会等会议做报告。
教育经历
2013.09-2019.01 复旦大学, 生命科学学院，生物化学系，博士；
2009.09-2013.06 兰州大学，生命科学学院，生物科学，学士
工作经历
2023.02-今 华南农业大学，教授
2019.4-2023.01 复旦大学，生命科学学院，博士后；
主持的科研课题
国家自然科学基金面上项目（在研2项）
国家自然科学基金青年科学基金
广州基础与应用基础研究专题科技菁英“领航”项目
第66批中国博士后科学基金面上项目
2019年度博士后创新人才支持计划
代表性论文（#一作，*通讯）（名字加黑）
1. Chang Y#, Chen Z#, Chen W#, Jin X, Wang X, Zhan H, Cao L, Wang H, Wang Y*,Wang C*, Sun B*. KNUCKLES promotes meiotic cell cycle progression by directly repressing the expression of KRP1 and KRP3 to ensure male fertility. Plant Commun(2025), 101610.
2. Wang C, Wang Y. Meiosis requires m6A modification for selection of targets in plants. New Phytologist,244(6), 2118–2120 (2024).
3. Wang C, Chen ZY, Copenhaver GP*, Wang YX*.Heterochromatin in plant meiosis. Nucleus, 2024, 15 (1): 2328719
4. Wang TY, Wang HK, Lian QC, Jia Q, You CJ, Copenhaver GP*;Wang C*; Wang YX*. HEI10 is Subject to Phase Separation and Mediates RPA1a Degradation during Meiotic Interference-sensitive Crossover Formation. Proc Natl Acad Sci U S A, 2023,120,(52): e2310542120.
5. Wang C, Li X, Huang J, Ma H, Wang C R, Wang YX*. Isolation of Meiocytes and Cytological Analyses of Male Meiotic Chromosomes in Soybean, Lettuce, and Maize. In: Riechmann, J.L., Ferrándiz, C. (eds) Flower Development.Methods Mol. Biol(book series). 2023;2686:219-239.
6. Li JC#, Wang C#, Liang W, Zhang J, Jiang CK, Liu Y, Ren Z, Ci D, Chang J, Han S, Deng XW, Wang YX*, Qian WQ*. Functional importance and divergence of plant apurinic/apyrimidinic endonucleases in somatic and meiotic DNA repair.Plant Cell. 2023; 35:2316-2331
7. Wang C#, Huang JY#, Li YP, Zhang J, He CP, Li TY, Jiang DH, Dong AW, Ma H*, Copenhaver GP*, Wang YX*; DNA Polymerase Epsilon Binds Histone H3.1-H4 and Recruits MORC1 to Mediate Meiotic Heterochromatin Condensation, Proc Natl Acad Sci U S A, 2022, 119(43):e2213540119. IF: 12.779
8. Wang C; Huang JY; Zhang J; Yu Y; Copenhaver GP; You CJ*; Wang YX*; DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot in Arabidopsis, Proc Natl Acad Sci U S A, 2022, 119(41):e2208441119. IF: 12.779
9. Huang JY#, Wang C#, Li X, Fang XL, Huang N, Wang Y, Ma H, Wang YX*, Copenhaver GP*. Conservation and divergence in the meiocyte sRNAomes of Arabidopsis, soybean and cucumber. Plant Physiology, 2020, 82:301-317.
10. Huang JY#, Wang C#, Wang HF, Lu PL, Zheng BL, Ma H, Copenhaver GP*, Wang YX*. Meiocyte-specific and AtSPO11-1-dependent small RNAs and their association with meiotic gene expression and recombination. Plant Cell, 2019, 31:1-21. In brief by the editor in the same issue.
11. Wang C#, Huang JY#, Zhang J, Wang HK, Han YP, Copenhaver GP, Ma H, Wang YX*. The Largest Subunit of DNA Polymerase Delta is Important for Normal Formation of Meiotic Type I Crossovers in Arabidopsis. Plant Physiology, 2019, 179: 446-459.
12. Huang JY#, Li X#, Wang C, Wang YX. Evaluation of Crossover Number, Distribution, and Interference Using Cytological Assays in Arabidopsis. Current Protocal, 2022, 1(12).
13. He CP#, Chen ZY#, Zhao YY, Yu Y, Wang HK, Wang C, Copenhaver GP, Ji Qi, Wang YX. Histone demethylase IBM1-mediated meiocyte gene expression ensures meiotic chromosome synapsis and recombination. PLoS Genet, 2022, 18:e1010041.
14. Huang JY#, Chenjiang You Cj#, Cong Wang C, Yingxiang Wang YX, and Copenhaver GP*. Identifying Small RNAs and Analyzing Their Association with Gene Expression Using Isolated Arabidopsis Male Meiocytes, Methods Mol Biol (book series), 2022, 2484:23-41
15. Wang HK#, Xu WY#, Sun YJ, Lian QC, Wang C, Yu CY, He CP, Wang J, Ma H, Copenhaver GP*, Wang YX*, The cohesin loader SCC2 contains a PHD finger that is required for meiosis in land plants. PLoS Genetics, 2020, 16(6): e1008849.
16. Huang JY#, Cheng ZH#, Wang C, Hong Y, Su H, Wang J, Copenhaver GP, Ma H*, Wang YX*, Formation of Interference-Sensitive Meiotic Cross-Overs Requires Sufficient DNA Leading-Strand Elongation, Proc Natl Acad Sci U S A, 2015, 112(40): 12534-12539.
17. 黄霁月; 王聪; 王应祥; 减数分裂重组的分子遗传机制研究进展及在作物育种中的应用, 华南农业大学学报, 2022, 43(6): 17-35
(2026年4月更新)
